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BANGKOK 19 July 2019 08:59

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Posted (edited)

Grapefruit  compounds known as furanocoumarins can block cytochrome P450 3A4 (CYP3A4) enzymes.,  so some of the medications may be broken down more slowly by the liver.   This can be an issue as your plasma drug concentration levels build up,  so that 1/2 of a pill the doctor prescribes 1 x a day,  may linger so long that it builds up faster than it is broken down.    So be careful.

 

I didn't know that pomelo had the same situation as grapefruit.    Where did you see that?   

Edited by samuttodd

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Makro frozen 100% lime juice.....no squeezing!....defrost decant and keep in the fridge.

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22 minutes ago, samuttodd said:

Grapefruit  compounds known as furanocoumarins can block cytochrome P450 3A4 (CYP3A4) enzymes.,  so some of the medications may be broken down more slowly by the liver.   This can be an issue as your plasma drug concentration levels build up,  so that 1/2 of a pill the doctor prescribes 1 x a day,  may linger so long that it builds up faster than it is broken down.    So be careful.

 

I didn't know that pomelo had the same situation as grapefruit.    Where did you see that?   

Harvard medical site q & a. I had been warned of this by a Dr in Australia before so I don’t eat grapefruit and just googled it when I saw this thread.

 

“From the handful of studies on the effects of pomelo on drug metabolism, it looks like pomelo and pomelo juice act much like grapefruit and grapefruit juice.

Grapefruit and pomelo aren't the only fruits that affect drug metabolism. Lab studies suggest that black mulberry juice, wild grape juice, pomegranate juice, and black raspberry juice also interfere with CYP3A4.

You have two basic options. One is to avoid eating pomelo and drinking pomelo juice. The other is to keep enjoying pomelo but talk with your doctor about switching to a statin that isn't affected by grapefruit, such as fluvastatin (Lescol), pravastatin (Pravachol), or rosuvastatin (Crestor).

— Thomas Lee, M.D.
Editor in Chief” 

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Or you've just discovered a way to double the mileage from your benzodiazapines.

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Posted (edited)

I come down on the other side of the coin than most. 

 

I worry about drinking too much water and sweating it out without replacing the electrolytes.  Literally, I went through liters and liters on a typical outdoor day in BKK, and I could tell I had some kind of imbalance going on...  Weakness, cramps, etc.  Plus, my black shirts (remember that year of wearing black?) would end up almost gray by the end of the day.  So I figured I was sweating out a lot of salts.

 

I started adding oral rehydration salts (ORS) to my bottled water.  At first, I bought the sugar free variety, but then discovered that the body needs some glucose to properly absorb the salts.  Blame Google for that one...  Eventually, I went with plain old sea salt and supplemented with fresh fruit to get the glucose.  That seemed to do the trick, and fresh fruit was so easy to find.

 

My memory isn't clear on the details- especially in light of misleading labeling, but soda water indicates it has some sodium in it, while sparkling water may just be carbonated, with God only knows what -or nothing at all- added to it.  So it's a good idea to read the label.

 

Edited by impulse

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2 hours ago, grollies said:

Absolutely fair enough mate and I'm not criticising you at all, we are all free to make our own decisions in life. I'm just posting my opinion which differs from yours. I wish you well. Sorry about the 'issues' comment, retracted.

We all have different opinions no problems here. I am happy you care about your health too. Not too many people take care of themselves. I did not get offended from the Issues comment no problems.

 

There is so much data out there on all kind of things we ourselves need to filter through it and see how bad or not bad something is. I try to avoid artificial sweeteners, but in those packages the dosage is real low. It just gives a minor taste to the water. 

 

If I did not have this I might have gone for some kind of syrup (worse). 

 

Its kinda like I love lifting weights but hate cardio. I do something that is similar to cardio (farmers walk) but not exactly. But farmers walk does not bore me and I keep doing it. If i were to go jogging or something like that I just would not keep it up. So sometimes doing something a little less perfect is better then the alternative doing nothing. 

 

Maybe that makes no sense to you but in my years of training I have learned its better to be consistent and maybe not perfect then go for perfect and give up early.

 

This is already a huge improvement from me sucking up ice tea and loads of syrup.. who knows maybe after I am used to this it might be easier to switch to pure water. 

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17 minutes ago, impulse said:

I come down on the other side of the coin than most. 

 

I worry about drinking too much water and sweating it out without replacing the electrolytes.  Literally, I went through liters and liters on a typical outdoor day in BKK, and I could tell I had some kind of imbalance going on...  Weakness, cramps, etc.  Plus, my black shirts (remember that year of wearing black?) would end up almost gray by the end of the day.  So I figured I was sweating out a lot of salts.

 

I started adding oral rehydration salts (ORS) to my bottled water.  At first, I bought the sugar free variety, but then discovered that the body needs some glucose to properly absorb the salts.  Blame Google for that one...  Eventually, I went with plain old sea salt and supplemented with fresh fruit to get the glucose.  That seemed to do the trick, and fresh fruit was so easy to find.

 

My memory isn't clear on the details- especially in light of misleading labeling, but soda water indicates it has some sodium in it, while sparkling water may just be carbonated, with God only knows what -or nothing at all- added to it.  So it's a good idea to read the label.

 

Salt is not as bad as most people thing, and I even take salt at times because i sweat so much normally and when training. Nothing worse then cramping up. If you get cramps you know you need to replenish your minerals. The stuff i drink has those minerals plus i take tablets for them too. I like you sweat a lot. I can drink 2 liters of water in an hour of training and then I don't have to go to the toilet to pee.. its all sweated out. 

 

I noticed the cramps and weakness too especially when i was walking with 2 25 kg weights around the park. Great exercise but if you are not well hydrated salts too you will feel weak and performance will go down. There are great articles about the need for salt. Not for the people who dont sweat or exercise... but those who do have greater needs.

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3 hours ago, grollies said:

Ok, but I would prefer personally to drink natural lime juice with water over chemicals made in a factory. My water comes from a borehole (water tested) and has plenty of mineral content.

 

My drink is totally sustainable as I grow the limes. I don't really get your point on 'sustainability' in this context.

 

I totally agree with you on the sugary drinks and have quit them a while ago. The sugar-free alternatives are just as bad for you.

 

BTW your lemon & lime drinks contain sugar but you know that.

 

Hmmm I don't think so. Those electrolyte packs are sugar free.

 

It is your limes that contain sugar. Quite significant amounts of it too.

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3 hours ago, robblok said:

With sustainable means me keep doing it not it being available of from yourself. My problem is that your solution squeezing limes and stuff bores me after a while. It takes effort (yes I am lazy) and not as nice and easy as just opening a package and mixing.

 

I usually buy lemons and limes in bulk, squeeze and freeze in ice cube trays.

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8 hours ago, thedemon said:

 

Hmmm I don't think so. Those electrolyte packs are sugar free.

 

It is your limes that contain sugar. Quite significant amounts of it too.

No way are you getting away with that.

 

On average, 100g of cola has 11g of sugar.

 

So a small (say 345ml) bottle of cola has 38g of sugar.

 

Lime juice contains 1.7g of sugar per 100g.

 

The equivalent 345ml bottle of lime juice would contain 6g of sugar.

 

Would I be likely to drink 1 or 2  small bottles of cola per day? Sure.

 

Would I be likely to drink 1 or 2 small bottles of lime juice (and, don't forget, we're talking freshly squeezed lime juice) per day? No way. Let's assume I'd drink 30ml of lime juice per day. That's around 0.5g sugar.

 

Your claim that the electrolyte drinks are sugar-free is rubbish, some have 'no added sugar' some have natural sweeteners like stevia. There are one or two products that are sugar-free but they are very expensive.

 

I'd be more concerned about people who install R/O water filters for their drinking water. That'll remove all trace minerals and start leeching minerals from your body. Plus they waste around 40% of water used in the process.

 

A balanced diet will provide all the vitamins and minerals you need. I do a lot of physical work and sweat a great deal. I drink plenty of our borehole water and eat well. I've recently cut out sugar drinks, rice, bread, pasta and potatoes (I'll have one meal per week with one of those carbs) and have substituted the carbs for lentils. I eat lots of yoghurt, fresh fruit, museli, nuts, garlic, ginger (Indian curries at least 3 times a week) and am already losing weigh and feeling better.

 

Refined sugar is really bad for you.

 

And to keep on topic, soda water with juice of 1 lime and ice is the only drink that really quenches my thirst. 

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Posted (edited)
20 hours ago, essox essox said:

why NOT just drink plain cool water.....????

Because Soda water has a bite like beer, and none of beers drawbacks, apart from gas.

I go through two crates a week. Agree that the glass bottles are ridiculous, especially since the two main brands can their own beer as well.

And Schweppes prices are a sick joke. But TIT.

On the health front, gassy water is the least of my concerns. 

Death and dying, in the app that is our life, it's not a bug it's a feature.

Edited by Small Joke
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12 hours ago, grollies said:

Papers? They'd be the release papers from the asylum? 

I have chosen to leave a highly functional society, democrazy and country,  and go ahead and live in Thailand. Figur that one out 🧐

 

a few bottles of bubbles, whant change much. 

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In regards to salt loss via perspiration,   If you are outdoors and active,  i wouldn't hold back on the salt at all.    You need it every bit as much as that water.

 

When I go for a spin on my bike,  lots of times I come back with dried salt on my face and neck from perspiration.   

 

I've taken a liking to salted fish with rice,  have it each day and reckon 1 salted fish steak has a gram of salt in it if not more.

 

Blood pressure is good, I also hit magnesium, calcium and zinc each day.   and eat foods high in potassium.   I try to bolster anything that is water soluable,  since I drink a freightcar load of soda water and sweat like a guy on trial.

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