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Efficacy of vaccines may reduce after mass inoculation – Dr. Yong


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Efficacy of vaccines may reduce after mass inoculation – Dr. Yong

 

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The efficacy of any vaccine, including COVID-19 vaccines, tends to be lower when used in the field to inoculate millions of people, when compared to the results produced during clinical trials, said Thai virologist Dr. Yong Poovorawan in his Facebook post on Friday.

 

He cited the case of a Hepatitis B vaccine, which its manufacturer claimed had efficacy of between 94-95%. When the vaccine was used in mass inoculations, however, its efficacy dropped to about 80%.

 

Likewise, he said, the 95% efficacy of a COVID-19 vaccine, asclaimed by Pfizer during the trial period, is likely to drop due to several variables.

 

Full story: https://www.thaipbsworld.com/efficacy-of-vaccines-may-reduce-after-mass-inoculation-dr-yong/

 

 

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The Title (which is from PBS and not created by TVF!) is misleading as it gives the impression that he is talking about  actual vaccine effectiveness changing, for example the virus mutating into a le

As I understand the Chinese vaccine Sinovac (which is still to be peer reviewed) has 50.4% efficacy so any significant drop would put them under the 50% cut off required by the WHO.

Just get the bloody vaccines out and into arms now Dr. Yong. Never mind wracking your brains to come up with hypothetical negatives. 

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1 hour ago, Sheryl said:

"And then what you see after mass administration is effectiveness under real world conditions."

But no indications at all so far that Thailand is even contemplating mass administration.

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1 hour ago, Sheryl said:

in clinical trials, protocols are meticulously followed - no mistakes in administration of the vaccine (vaccine reconstituted with exactly the recommended type and amount of solvent, exact amount given exactly as recommend) , no varying from the recommended schedule.

You mean like the dosage stuff up by Astra Zeneca during trials?

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2 hours ago, FarFlungFalang said:

You mean like the dosage stuff up by Astra Zeneca during trials?

People make mistakes, that's life.

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2 minutes ago, ukrules said:

People make mistakes, that's life.

Yes they do and in this case it was fortunate that this mistake led to the discovery that was an increase in the efficacy.

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