webfact Posted June 14, 2021 Share Posted June 14, 2021 Human trials of the first Thai COVID-19 vaccine, developed by Chula Vaccine Research Centre (CVRC) at Chulalongkorn University and King Chulalongkorn Memorial Hospital, began today (Monday). Called “ChulaCov19”, it is the first vaccine developed in Thailand, but will be the second to be locally made, if approved, after Siam Bioscience’s production of the UK’s AstraZeneca vaccine. It is also an mRNA vaccine, a type that provides instructions to human cells on how to make a “spike protein” that triggers the body’s immune response. Full story: https://www.thaipbsworld.com/human-trials-of-first-thai-developed-covid-19-vaccine-begins-monday/ -- © Copyright Thai PBS 2021-06-15 - Whatever you're going through, the Samaritans are here for you - Follow Thaivisa on LINE for breaking COVID-19 updates 1 1 Link to comment Share on other sites More sharing options...
RichardColeman Posted June 14, 2021 Share Posted June 14, 2021 40 minutes ago, webfact said: Called “ChulaCov19” Sounds like something from Jive Bunny ! 1 1 Link to comment Share on other sites More sharing options...
Popular Post Albert Zweistein Posted June 14, 2021 Popular Post Share Posted June 14, 2021 They copied AZ ? 4 Link to comment Share on other sites More sharing options...
Popular Post kotsak Posted June 14, 2021 Popular Post Share Posted June 14, 2021 Just now, Albert Zweistein said: They copied AZ ? AZ is not an mRNA unless they got confused which wouldn't be surprising.. ???? 3 3 Link to comment Share on other sites More sharing options...
Albert Zweistein Posted June 14, 2021 Share Posted June 14, 2021 11 minutes ago, kotsak said: AZ is not an mRNA unless they got confused which wouldn't be surprising.. ???? Exactly what I mean. 2 Link to comment Share on other sites More sharing options...
gargamon Posted June 14, 2021 Share Posted June 14, 2021 Ahh, so this is what they're using on the foreigners...???? 2 Link to comment Share on other sites More sharing options...
Popular Post ezzra Posted June 14, 2021 Popular Post Share Posted June 14, 2021 All i can wish those who will get the Thai vaccine is GOOOD Luck to them, they are brave people... 2 2 Link to comment Share on other sites More sharing options...
Popular Post Bkk Brian Posted June 14, 2021 Popular Post Share Posted June 14, 2021 Prayut back in Jan: Thailand’s PM is saying he won’t let Thai people become vaccine “guinea pigs” in his Facebook post today as he points to reports of serious negative side effects that some people have suffered after getting jabbed with the Covid-19 vaccine. https://thethaiger.com/news/national/thailands-pm-says-he-wont-let-thais-become-vaccine-guinea-pigs From the article link in th OP "The first phase involves 72 volunteers. Half are aged 18-55 and half 65-75. Some of them will get 10 micrograms (mcg) of the vaccine, while others will get 25mcg and 50mcg, to determine the most effective dosage. The second phase, involving 150-300 volunteers, will begin in August, if the first phase results are satisfactory. If both phases of the trial prove high efficacy and safety of the vaccine, the third phase can be skipped and it could be approved for mass production before mid-2022, said Dr. Suttipong." 4 1 1 4 Link to comment Share on other sites More sharing options...
Popular Post J Town Posted June 14, 2021 Popular Post Share Posted June 14, 2021 This is most likely the reason for bungling all other attempts. There's gold in them thar shots and those in power want that gold. 4 Link to comment Share on other sites More sharing options...
Popular Post Crossy Posted June 14, 2021 Popular Post Share Posted June 14, 2021 Quote If both phases of the trial prove high efficacy and safety of the vaccine, the third phase can be skipped and it could be approved for mass production before mid-2022, said Dr. Suttipong. So, let me get this right, they are going to go full-bore production based upon the results from a sample size less than 400? I think I would be placing this in the "unwise" box, the Western jabs have been hurried through but this borders on madness. 10 2 Link to comment Share on other sites More sharing options...
nightfox Posted June 15, 2021 Share Posted June 15, 2021 Human trials is just a nice saying for guinea pigs. Link to comment Share on other sites More sharing options...
ThomasThBKK Posted June 15, 2021 Share Posted June 15, 2021 54 minutes ago, J Town said: This is most likely the reason for bungling all other attempts. There's gold in them thar shots and those in power want that gold. No. No. This was not supported by the government, they literally don't want this to succeed. Chula and mahidol are decent labs. They complain about those <deleted> in power all the time. They begged for some funding and got nothing... 2 Link to comment Share on other sites More sharing options...
Popular Post realfunster Posted June 15, 2021 Popular Post Share Posted June 15, 2021 41 minutes ago, Crossy said: So, let me get this right, they are going to go full-bore production based upon the results from a sample size less than 400? I think I would be placing this in the "unwise" box, the Western jabs have been hurried through but this borders on madness. Fully agree mate. It rings of ‘local’ propaganda and these scientists trying to remain relevant. That’s a tiny sample group and then they plan to possibly skip phase three for approval (whatever that means - by mid 2022). That is a year from now and production is not even mentioned…. The haste seems unnecessary as they have already missed the worst of the global outbreak, and although it is likely ongoing COVID vaccines may be required for some time, already established vaccines will be flooding the market by early next year. As for local use, well I presume even the delayed AZ from SB will be pumping out tens of millions of doses a month come year-end. So, I doubt come mid-2022 anyone is going to be particularly interested in a hastily approved, phase-3 skipping, tiny sample sized vaccine from Chula. 4 Link to comment Share on other sites More sharing options...
hotchilli Posted June 15, 2021 Share Posted June 15, 2021 2 hours ago, gargamon said: Ahh, so this is what they're using on the foreigners...???? Not this one. 1 Link to comment Share on other sites More sharing options...
Popular Post bradiston Posted June 15, 2021 Popular Post Share Posted June 15, 2021 4 minutes ago, RobMuir said: With people dropping off like flies with the Brit-swede Astrazeneca muck from blood clots, the Chinese syrup being quite ineffective, the USA Johnson and Johnson balls up and the impractical Pfizer rush job I am hopeful that the Thais will come up with something better. Live in hope, die in hope. More poison in your post than in any vax. 5 5 1 Link to comment Share on other sites More sharing options...
Popular Post Excel Posted June 15, 2021 Popular Post Share Posted June 15, 2021 10 minutes ago, RobMuir said: With people dropping off like flies with the Brit-swede Astrazeneca muck from blood clots, the Chinese syrup being quite ineffective, the USA Johnson and Johnson balls up and the impractical Pfizer rush job I am hopeful that the Thais will come up with something better. Yes what they really need is another Alexander Fleming type but I doubt the Thais have anyone of that ilk, the bum gun is about the Thai level of innovation. 3 Link to comment Share on other sites More sharing options...
spidermike007 Posted June 15, 2021 Share Posted June 15, 2021 This might have made sense if the trials started on April 2nd, 2020. But now? Why even bother? Just admit defeat, for once in your lives. Stop with the lies and deceptions. 1 1 Link to comment Share on other sites More sharing options...
mtls2005 Posted June 15, 2021 Share Posted June 15, 2021 The project is a joint venture between Prof Kiat Ruxrungtham from the Center of Excellence in Vaccine Research Center and Development (ChulaVRC) and Professor Drew Weissman from the University of Pennsylvania. The vaccine will use mRNA technology to trigger an immune response against Covid-19, similar to the Pfizer-BioNTech and Moderna shots. https://www.chula.ac.th/en/clipping/47302/ 1 Link to comment Share on other sites More sharing options...
Bkk Brian Posted June 15, 2021 Share Posted June 15, 2021 1 minute ago, RobMuir said: Hope he can help. I don't think it could have been done without him seeing as he sent the prototype Link to comment Share on other sites More sharing options...
TheFishman1 Posted June 15, 2021 Share Posted June 15, 2021 He didn’t tie and then the vaccine for aids didn’t tie and then the vaccine for cancer and treatment so what’s next amazing Thailand TIT 1 Link to comment Share on other sites More sharing options...
Popular Post sathornlover Posted June 15, 2021 Popular Post Share Posted June 15, 2021 3 hours ago, Bkk Brian said: Prayut back in Jan: Thailand’s PM is saying he won’t let Thai people become vaccine “guinea pigs” in his Facebook post today as he points to reports of serious negative side effects that some people have suffered after getting jabbed with the Covid-19 vaccine. https://thethaiger.com/news/national/thailands-pm-says-he-wont-let-thais-become-vaccine-guinea-pigs From the article link in th OP "The first phase involves 72 volunteers. Half are aged 18-55 and half 65-75. Some of them will get 10 micrograms (mcg) of the vaccine, while others will get 25mcg and 50mcg, to determine the most effective dosage. The second phase, involving 150-300 volunteers, will begin in August, if the first phase results are satisfactory. If both phases of the trial prove high efficacy and safety of the vaccine, the third phase can be skipped and it could be approved for mass production before mid-2022, said Dr. Suttipong." When one reads something like this, one would not believe one's own eyes and senses if one completely forgets or does not know where this "vaccine development" is supposed to take place. For comparison, I would like to refer to the long suffering of the Curevac vaccine, which presumably offers the same protection at a significantly lower dosage as the other successful mRNA vaccines and another advantage is that the active substance remains stable at a temperature of five degrees for at least three months. Unfortunately, the 2-3rd phase only started in December 2020 and not enough infections could be detected in April-May as planned: „The company said on May 28 that the late-stage trial involving about 40,000 volunteers in Europe and Latin America had reached a first interim analysis at 59 COVID-19 cases, but that more data would be necessary for statistically reliable efficacy numbers.“ But in fact at least 160 cases are needed, in Thailand this does not seem to be necessary. Who would trust a vaccine where the proof of efficacy is completely lacking and the side effects are virtually unexplored due to the small number of test persons? EU regulator does not expect approval for CureVac vaccine before August 3 Link to comment Share on other sites More sharing options...
herfiehandbag Posted June 15, 2021 Share Posted June 15, 2021 (edited) 2 hours ago, ThomasThBKK said: No. No. This was not supported by the government, they literally don't want this to succeed. Chula and mahidol are decent labs. They complain about those <deleted> in power all the time. They begged for some funding and got nothing... That is very interesting. If it works ( and I know nothing about the capabilities of the labs or scientists involved, but I hear what you say) I wonder under which (whose) auspices it will be put into production! I read subsequently that they have a company lined up to produce it. That will of course have to be licenced, and as it will challenge a very important monopoly I could predict a problem there. There may be gracious permission to produce it in an existing facility though, taking into account all the circumstances... Edited June 15, 2021 by herfiehandbag 2 Link to comment Share on other sites More sharing options...
clivebaxter Posted June 15, 2021 Share Posted June 15, 2021 (edited) 2 hours ago, RobMuir said: With people dropping off like flies with the Brit-swede Astrazeneca muck from blood clots, the Chinese syrup being quite ineffective, the USA Johnson and Johnson balls up and the impractical Pfizer rush job I am hopeful that the Thais will come up with something better. How is 32 deaths in the UK out of over 21 million dropping like flies? https://medicalxpress.com/news/2021-04-uk-deaths-clots-az-jabs.html Edited June 15, 2021 by clivebaxter 2 Link to comment Share on other sites More sharing options...
fondue zoo Posted June 15, 2021 Share Posted June 15, 2021 Everyone wants a piece of the covid cake. 1 Link to comment Share on other sites More sharing options...
ThomasThBKK Posted June 15, 2021 Share Posted June 15, 2021 13 minutes ago, herfiehandbag said: That is very interesting. If it works ( and I know nothing about the capabilities of the labs or scientists involved, but I hear what you say) I wonder under which (whose) auspices it will be put into production! So far the samples are produced in the USA. I am sure there will be some asian producer if it works out, hopefully outside of Thailand in Singapore, Korea or so.... Link to comment Share on other sites More sharing options...
Boedog Posted June 15, 2021 Share Posted June 15, 2021 Start to human trials nothing like skipping the animal trials, l wonder how this will turn out Link to comment Share on other sites More sharing options...
Hanuman2547 Posted June 15, 2021 Share Posted June 15, 2021 Luckily I have already been vaccinated with the Pfizer vaccine. I'd pass on the Thai developed vaccine. Link to comment Share on other sites More sharing options...
Heng Posted June 15, 2021 Share Posted June 15, 2021 It seems every other day there is a news bit that says 'just fly to vaccinate and get it over with.' Link to comment Share on other sites More sharing options...
Dont confuse me Posted June 15, 2021 Share Posted June 15, 2021 Just when you thought things couldn't get more screwed up! You couldn't make this comedy of errors up! The government is a shambles and it's dragging the country down with it Link to comment Share on other sites More sharing options...
placnx Posted June 15, 2021 Share Posted June 15, 2021 5 hours ago, realfunster said: Fully agree mate. It rings of ‘local’ propaganda and these scientists trying to remain relevant. That’s a tiny sample group and then they plan to possibly skip phase three for approval (whatever that means - by mid 2022). That is a year from now and production is not even mentioned…. The haste seems unnecessary as they have already missed the worst of the global outbreak, and although it is likely ongoing COVID vaccines may be required for some time, already established vaccines will be flooding the market by early next year. As for local use, well I presume even the delayed AZ from SB will be pumping out tens of millions of doses a month come year-end. So, I doubt come mid-2022 anyone is going to be particularly interested in a hastily approved, phase-3 skipping, tiny sample sized vaccine from Chula. If the problem is a lack of money for Phase 3, why not appeal to Gates Foundation or GAVI? Of course by the time Phase 2 is done, it may be difficult to find study subjects who have not been exposed to Covid or been previously vaccinated, but there will still probably be many other countries with low vaccination rates for doing Phase 3 trials. With sufficient know how, by middle of next year they should be prepared to tweak the vaccine just as Pfizer and Moderna are doing to account for new variants. Then this vaccine can function as a booster for AZ. Link to comment Share on other sites More sharing options...
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